BDBM50631208 CHEMBL5438135

SMILES N[C@H](CO)Cc1nc(no1)-c1ccc(Oc2ncc(Cl)cc2F)cc1

InChI Key InChIKey=WTLHYZBMCZYJLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50631208   

TargetLeukotriene A-4 hydrolase(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50631208(CHEMBL5438135)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of LTA4H (unknown origin) using Arg-AMC as substrate preincubated with compound for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50631208(CHEMBL5438135)
Affinity DataIC50: 120nMAssay Description:Inhibition of LTA4H in human whole blood assessed as ionophore-stimulated LTB4 release preincubated for 15 mins by competitive immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed