BDBM50631309 CHEMBL5188976

SMILES CCOc1cc(ccc1O)/C=C\2/C(=O)NC(=S)S2

InChI Key InChIKey=BLHXTUCOFJOMCR-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50631309   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631309(CHEMBL5188976)
Affinity DataIC50: 46nMAssay Description:Inhibition of His-tagged full-length human DYRK2 (127 to 485 residues) expressed in Escherichia coli incubated for 10 min in presence of ATP by liqui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631309(CHEMBL5188976)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant DYRK1A (unknown origin) using DYRKtide as substrate incubated for 2 hrs in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-3(Human)
Joint Research Institution of Altitude Health and Institute of Respiratory Health and National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50631309(CHEMBL5188976)
Affinity DataIC50: 170nMAssay Description:Inhibition of PIM3 (unknown origin) by FRET based Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Joint Research Institution of Altitude Health and Institute of Respiratory Health and National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50631309(CHEMBL5188976)
Affinity DataIC50: 310nMAssay Description:Inhibition of PIM2 (unknown origin) by FRET based Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Joint Research Institution of Altitude Health and Institute of Respiratory Health and National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50631309(CHEMBL5188976)
Affinity DataIC50: 420nMAssay Description:Inhibition of PIM1 (unknown origin) by FRET based Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed