BDBM50631442 CHEMBL5411315

SMILES Nc1ccccc1NC(=O)c1ccc(CNC(=O)OC2CCN(CC2)S(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)cc1

InChI Key InChIKey=JGJZNWDPKNHILY-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50631442   

TargetHistone deacetylase 1(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631442(CHEMBL5411315)
Affinity DataIC50: 109nMAssay Description:Inhibition of HDAC1 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound for 6 hrs followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631442(CHEMBL5411315)
Affinity DataIC50: 143nMAssay Description:Inhibition of full length recombinant human HDAC3 expressed in Sf9 cells using 6-carboxyfluorescein peptide as substrate preincubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631442(CHEMBL5411315)
Affinity DataIC50: 154nMAssay Description:Inhibition of HDAC2 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound for 6 hrs followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631442(CHEMBL5411315)
Affinity DataIC50: 242nMAssay Description:Inhibition of HDAC1 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound followed by substrate addition by ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631442(CHEMBL5411315)
Affinity DataIC50: 327nMAssay Description:Inhibition of HDAC2 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound for 2 hrs followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631442(CHEMBL5411315)
Affinity DataIC50: 808nMAssay Description:Inhibition of HDAC2 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound followed by substrate addition by ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631442(CHEMBL5411315)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in Sf9 cells using 6-carboxyfluorescein peptide as substrate preincubated with compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631442(CHEMBL5411315)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC4 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound for 6 hrs followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631442(CHEMBL5411315)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length recombinant human HDAC8 expressed in Sf9 cells using 6-carboxyfluorescein peptide as substrate preincubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631442(CHEMBL5411315)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length recombinant human HDAC6 expressed in Sf9 cells using 6-carboxyfluorescein peptide as substrate preincubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631442(CHEMBL5411315)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound for 6 hrs followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631442(CHEMBL5411315)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC9 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound for 6 hrs followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631442(CHEMBL5411315)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound for 6 hrs followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631442(CHEMBL5411315)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC10 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound for 6 hrs followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed