BDBM50631450 CHEMBL5421177

SMILES COc1cccc(c1)[C@H]1[C@@H](N[C@@H](CC(C)(C)C)[C@]1(CN)c1ccc(Cl)cc1F)C(=O)Nc1ccc(cc1OC)C(O)=O

InChI Key InChIKey=NBYBNLXKIUYRBI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50631450   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50631450(CHEMBL5421177)
Affinity DataKi:  47nMAssay Description:Inhibition of MDM2 (1 to 118 residues)/p53 (unknown origin) interaction expressed in Escherichia coli BL21(DE3) cells assessed as inhibition constant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50631450(CHEMBL5421177)
Affinity DataKi:  2.76E+4nMAssay Description:Inhibition of MDM4 (14 to 111 residues)/p53 (unknown origin) interaction expressed in Escherichia coli BL21(DE3) cells assessed as inhibition constan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed