BDBM50631496 CHEMBL5404648

SMILES OC(=O)[C@@H]1C[C@H]1c1nc(c(o1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F)-c1ccccc1

InChI Key InChIKey=CRLZRGXSDBAEFD-UHFFFAOYSA-N

Data  1 Kd  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50631496   

TargetRetinoic acid receptor RXR-gamma(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50631496(CHEMBL5404648)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at full length human RXR gamma expressed in HEK293T cells measured after 16 hrs by Dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50631496(CHEMBL5404648)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at full length human RXR beta expressed in HEK293T cells measured after 16 hrs by Dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50631496(CHEMBL5404648)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at full length human RXR alpha expressed in HEK293T cells measured after 16 hrs by Dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50631496(CHEMBL5404648)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at full length human RXR beta expressed in HEK293T cells measured after 16 hrs by Dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50631496(CHEMBL5404648)
Affinity DataEC50:  4nMAssay Description:Agonist activity at full length human RXR gamma expressed in HEK293T cells measured after 16 hrs by Dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50631496(CHEMBL5404648)
Affinity DataEC50:  5nMAssay Description:Agonist activity at full length human RXR alpha expressed in HEK293T cells measured after 16 hrs by Dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50631496(CHEMBL5404648)
Affinity DataKd: <10nMAssay Description:Binding affinity to RXR alpha LBD (unknown origin) assessed as dissociation constant at 25 degree C by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed