BDBM50631498 CHEMBL5399947

SMILES C\C(=C/c1nc(c(o1)-c1ccccc1)-c1ccccc1)C(O)=O

InChI Key InChIKey=OYWOTPQUBJKMEN-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50631498   

TargetRetinoic acid receptor RXR-beta(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50631498(CHEMBL5399947)
Affinity DataEC50:  910nMAssay Description:Agonist activity at full length human RXR beta expressed in HEK293T cells measured after 16 hrs by Dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50631498(CHEMBL5399947)
Affinity DataEC50:  930nMAssay Description:Agonist activity at full length human RXR alpha expressed in HEK293T cells measured after 16 hrs by Dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50631498(CHEMBL5399947)
Affinity DataEC50:  930nMAssay Description:Agonist activity at Gal4-fused human RXRalpha transfected in HEK293T cells incubated for 16 hrs by firefly/renilla based Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50631498(CHEMBL5399947)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at full length human RXR gamma expressed in HEK293T cells measured after 16 hrs by Dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig-Maximilians-University of Munich

Curated by ChEMBL
LigandPNGBDBM50631498(CHEMBL5399947)
Affinity DataIC50: 2.40E+4nMAssay Description:Inverse agonist activity at Gal4-fused human full length Nurr1 LBD transfected in HEK293T cells assessed as suppression of Nurr1 activation incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed