BDBM50631635 CHEMBL5432640

SMILES Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCN1CC3(CCC(c4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)CC3)C1)c1nnc(C)n1-2

InChI Key InChIKey=JFSVSFBLGUFRRC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50631635   

TargetProtein cereblon(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631635BDBM50631635(CHEMBL5432640)
Affinity DataIC50: 21nMAssay Description:Binding affinity to Nano-Luc fused CRBN (unknown origin) expressed in digitonin-permeabilized HEK293 cells incubated for 10 mins by NanoBRET target e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631635BDBM50631635(CHEMBL5432640)
Affinity DataIC50: 287nMAssay Description:Binding affinity to Nano-Luc fused CRBN (unknown origin) expressed in live HEK293 cells incubated for 30 mins by NanoBRET target engagement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed