BDBM50631771 CHEMBL5438242

SMILES C[C@@H]1Oc2cc(cnc2N)-c2c(CCCOc3ccc(F)cc13)n(C)nc2C#N

InChI Key InChIKey=YKMRDBPMPYXBOZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50631771   

TargetALK tyrosine kinase receptor(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631771(CHEMBL5438242)
Affinity DataKi: <0.100nMAssay Description:Binding affinity to ALK (unknown origin) assessed as inhibition of constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631771(CHEMBL5438242)
Affinity DataKi:  0.620nMAssay Description:Binding affinity to ALK L1196M mutant (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed