BDBM50631890 CHEMBL5427695

SMILES COc1cccc(N2CCN(CC[C@H]3CC[C@H](NC(=O)N(C)C)CC3)CC2)c1F

InChI Key InChIKey=MUUSXXFKLPMJKL-UHFFFAOYSA-N

Data  8 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50631890   

TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631890BDBM50631890(CHEMBL5427695)
Affinity DataKi:  9.40nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor in HEK293 cell membranes measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2B(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631890BDBM50631890(CHEMBL5427695)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]-5-HT from 5HT2B receptor in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631890BDBM50631890(CHEMBL5427695)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631890BDBM50631890(CHEMBL5427695)
Affinity DataKi:  134nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor in HEK293 cell membranes measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631890BDBM50631890(CHEMBL5427695)
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [3H]-spiperone from D4 receptor in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631890BDBM50631890(CHEMBL5427695)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-5-HT from 5HT2C receptor in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631890BDBM50631890(CHEMBL5427695)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-SCH23390 from D1 receptor in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631890BDBM50631890(CHEMBL5427695)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-5-HT from 5HT2A receptor in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed