BDBM50632125 CHEMBL5425790

SMILES CC(CO)Nc1cc(CNc2nc(Nc3cc(C)[nH]n3)c3cnn(C4CCOCC4)c3n2)ccc1F

InChI Key InChIKey=AVDISIKMHVXATN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50632125   

TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632125(CHEMBL5425790)
Affinity DataIC50: 13nMAssay Description:Inhibition of TRKA (unknown origin) using TK peptide as substrate incubated for 30 mins in presence of ATP by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632125(CHEMBL5425790)
Affinity DataIC50: 24nMAssay Description:Inhibition of PLK4 (unknown origin) incubated for 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed