BDBM50632163 CHEMBL5432075

SMILES C\C(=C/C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N1CCCc2ccccc12)C(C)(C)C)c1ccc(cc1)C(F)(F)P(O)(O)=O

InChI Key InChIKey=ASMXVFULAKANJS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50632163   

TargetSignal transducer and activator of transcription 6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50632163(CHEMBL5432075)
Affinity DataKi:  3.40E+3nMAssay Description:Binding affinity to STAT6 SH2 domain (unknown origin) assessed as inhibition constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 5B(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50632163(CHEMBL5432075)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to STAT5B (unknown origin) assessed as inhibition constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50632163(CHEMBL5432075)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to N-terminal 6his-tagged human STAT5A (136 to 705 residues) expressed in Escherichia coli BL21-DE3 rosetta cells assessed as inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed