BDBM50632259 CHEMBL5395577

SMILES CCCOC(=O)c1sc(NC(=O)C[C@H](CCCNC(=O)CCCCC[N+]2=C(/C=C/C=C/C=C3/N(C)c4ccc(S(=O)(=O)O)cc4C3(C)C)C(C)(C)c3cc(S(=O)(=O)O)ccc32)NC(=O)c2cccc(-c3noc(C)n3)c2)nc1C

InChI Key InChIKey=OKRADMZDWCYHHR-UHFFFAOYSA-O

Data  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50632259   

TargetKinesin-like protein KIFC1(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632259BDBM50632259(CHEMBL5395577)
Affinity DataIC50: 257nMAssay Description:Inhibition of N-terminal His-tagged full length recombinant human HSET assessed as inhibition of microtubule-stimulated ATPase activity incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetKinesin-like protein KIFC1(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632259BDBM50632259(CHEMBL5395577)
Affinity DataKd:  315nMAssay Description:Binding affinity to N-terminal His-tagged full length recombinant human HSET assessed as dissociation constant incubated for 3 hrs in presence of 7 u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetKinesin-like protein KIFC1(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632259BDBM50632259(CHEMBL5395577)
Affinity DataKd:  332nMAssay Description:Binding affinity to N-terminal His-tagged full length recombinant human HSET assessed as dissociation constant incubated for 3 hrs in presence of 70 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetKinesin-like protein KIFC1(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632259BDBM50632259(CHEMBL5395577)
Affinity DataKd:  371nMAssay Description:Binding affinity to N-terminal His-tagged full length recombinant human HSET assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed