BDBM50632395 CHEMBL5415232

SMILES Nc1nn(nc1C(=O)NCc1ccc(cc1)C(=O)NO)-c1ccccc1

InChI Key InChIKey=NRYKLRJVRBXJSZ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50632395   

TargetHistone deacetylase 1(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50632395(CHEMBL5415232)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50632395(CHEMBL5415232)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of HDAC6 (unknown origin) assessed as release of fluorogenic AMC preincubated for 15 mins followed by addition of trypsin and substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50632395(CHEMBL5415232)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of HDAC1 (unknown origin) assessed as release of fluorogenic AMC preincubated for 15 mins followed by addition of trypsin and substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50632395(CHEMBL5415232)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of HDAC2 (unknown origin) assessed as release of fluorogenic AMC preincubated for 15 mins followed by addition of trypsin and substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50632395(CHEMBL5415232)
Affinity DataIC50: 6nMAssay Description:Inhibition of HDAC3 (unknown origin) assessed as release of fluorogenic AMC preincubated for 15 mins followed by addition of trypsin and substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50632395(CHEMBL5415232)
Affinity DataIC50: 195nMAssay Description:Inhibition of HDAC8 (unknown origin) assessed as release of fluorogenic AMC preincubated for 15 mins followed by addition of trypsin and substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50632395(CHEMBL5415232)
Affinity DataIC50: 751nMAssay Description:Inhibition of HDAC7 (unknown origin) assessed as release of fluorogenic AMC preincubated for 15 mins followed by addition of trypsin and substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50632395(CHEMBL5415232)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of HDAC9 (unknown origin) assessed as release of fluorogenic AMC preincubated for 15 mins followed by addition of trypsin and substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50632395(CHEMBL5415232)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of HDAC4 (unknown origin) assessed as release of fluorogenic AMC preincubated for 15 mins followed by addition of trypsin and substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50632395(CHEMBL5415232)
Affinity DataIC50: 6.42E+3nMAssay Description:Inhibition of HDAC5 (unknown origin) assessed as release of fluorogenic AMC preincubated for 15 mins followed by addition of trypsin and substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed