BDBM50632787 CHEMBL5437560

SMILES COc1cc2c(cc1OC)CN(C(=O)c1cc3cc(-c4ccc(NC(=O)c5ccc(C(F)(F)F)cc5)cc4)ccc3[nH]1)CC2

InChI Key InChIKey=JXKKCGLVWSFNAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50632787   

TargetATP-dependent translocase ABCB1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632787BDBM50632787(CHEMBL5437560)
Affinity DataIC50: 28nMAssay Description:Inhibition of P-gp-mediated multidrug resistance in doxorubicin-resistant human MCF7/ADR cells assessed as potentiation of doxorubicin-induced cytoto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed