BDBM50632884 CHEMBL5435411
SMILES CCn1nc(C)cc1C(=O)Nc1nc2cc(cc(OC)c2n1CCCNc1ncc(o1)-c1ccccc1C(F)(F)F)C(N)=O
InChI Key InChIKey=SAIPDXPIJPBWOT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50632884
Affinity DataKd: 0.789nMAssay Description:Binding affinity to His-tagged wild type human STING C-terminal domain (149 to 379 residues) expressed in Escherichia coli BL21 (DE3) cells assessed ...More data for this Ligand-Target Pair
Affinity DataEC50: 53nMAssay Description:Agonist activity at STING in human 293-Dual hSTING-R232 cells assessed as IRF3 activation by measuring ISRE-inducible SEAP activity by QUANTI-Blue as...More data for this Ligand-Target Pair
Affinity DataEC50: 116nMAssay Description:Agonist activity at STING in human 293-Dual hSTING-R232 cells assessed as INF-beta activation by measuring lucia luciferase activity by QUANTI-Blue a...More data for this Ligand-Target Pair
