BDBM50632919 CHEMBL5408234

SMILES CN(C)c1ccc(Nc2nc(Nc3cccc(NC(=O)C=C)c3)c3cc(Cl)ccc3n2)cc1

InChI Key InChIKey=OTJLWCBPTNMDHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50632919   

TargetEpidermal growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50632919(CHEMBL5408234)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human partial length EGFR (R669 to V1011 residues) L858R/T790M mutant expressed in mammalian expression system by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed