BDBM50632969 CHEMBL5404933

SMILES [2H]C([2H])([2H])Oc1cccc(c1)-c1cc(F)c(NC(=O)C2=C(CCC2)C(=O)N(C)O)c(F)c1

InChI Key InChIKey=ZPEHKMMPAKZUAK-BMSJAHLVSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50632969   

TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig Maximilian University of Munich

Curated by ChEMBL
LigandPNGBDBM50632969(CHEMBL5404933 | US20250066290, Example 4/10)
Affinity DataEC50:  5.80E+3nMAssay Description:Agonist activity at human Nurr1-LBD transfected in HEK293T cells co-transfected with pFR-Luc/pRL-SV40 assessed as transfection efficiency by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
LigandPNGBDBM50632969(CHEMBL5404933 | US20250066290, Example 4/10)
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro inhibition of hDHODH was measured using an N-terminally truncated recombinant hDHODH enzyme as described in J. Med. Chem. 2006; 49:1239....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2025
Entry Details
US Patent

LigandPNGBDBM50632969(CHEMBL5404933 | US20250066290, Example 4/10)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant DHODH by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed