BDBM50633011 CHEMBL5409419

SMILES COc1cccc2c3CCN(CCCCOc4ccc5CCC(=O)Nc5c4)Cc3oc12

InChI Key InChIKey=UCGXXGOWEGSYJJ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50633011   

Target5-hydroxytryptamine receptor 1A(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]-LSD from 5-HT1A receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligand competitive bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]N-methylspiperone from Dopamine D3 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]N-methylspiperone from Dopamine D4 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]-SCH23390 from Dopamine D1 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligand compet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]N-methylspiperone from Dopamine D2 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  113nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(1B) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  159nMAssay Description:Displacement of [3H]N-methylspiperone from Dopamine D5 receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  611nMAssay Description:Displacement of [3H]-LSD from 5-HT2C receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligand competitive bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  1.11E+3nMAssay Description:Displacement of [3H]-LSD from 5-HT2A receptor (unknown origin) expressed in HEK293T cell membrane incubated for 2 hrs by radioligand competitive bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  1.11E+3nMAssay Description:Table 5: The affinity of the compounds of the present disclosure for 5-HT2A receptors was determined by a radioligand competition binding assay. In t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent