BDBM50633041 CHEMBL5440386

SMILES CC#C[C@@H](CC(O)=O)c1ccc(cc1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=AFPNEBYEAGGIPJ-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50633041   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50633041(CHEMBL5440386)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma (unknown origin) transfected in HEK293 cells incubated for 18 hrs by based dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50633041(CHEMBL5440386)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at pBIND-PPARalpha (unknown origin) transfected in HepG2 cells incubated for 18 hrs by dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50633041(CHEMBL5440386)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR-LBD (unknown origin) using fluorescein-coactivator peptide by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50633041(CHEMBL5440386)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARdelta (unknown origin) transfected in HepG2 cells incubated for 18 hrs by dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50633041(CHEMBL5440386)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate incubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50633041(CHEMBL5440386)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human COX-1 using arachidonic acid as substrate incubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed