BDBM50633480 CHEMBL5402923

SMILES COc1ccc(NC(=O)Nc2nonc2\C(Nc2ccc(F)c(Br)c2)=N\O)cc1

InChI Key InChIKey=UTMDGFZKEHAVHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633480   

TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50633480(CHEMBL5402923)
Affinity DataIC50: 148nMAssay Description:Inhibition of human recombinant IDO1 assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50633480(CHEMBL5402923)
Affinity DataIC50: 44nMAssay Description:Inhibition of IDO1 in IFN-gamma-induced human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed