BDBM50633507 CHEMBL5403202

SMILES COc1cc2nn(CC(=O)N3CCOCC3)cc2cc1NC(=O)c1cccc(n1)[C@H](O)C(F)(F)F

InChI Key InChIKey=UZYWWOWQGPMEIC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633507   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer

Curated by ChEMBL

LigandBDBM50633507(CHEMBL5403202)Copy SMILESCopy InChI

Affinity DataIC50: 158nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human IRAK4 expressed in baculovirus infected Hi-5 cells using biotinylated-Ahx-KKARFSRFAGSSPSQASFAEP...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Bayer

Curated by ChEMBL

LigandBDBM50633507(CHEMBL5403202)Copy SMILESCopy InChI

Affinity DataIC50: 521nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human FLT3 (564 to end residues) expressed in Sf21 cells using biotinylated-Ahx-GGEEEEYFELVKKKK pepti...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL