BDBM50633514 CHEMBL5412519

SMILES COc1cc2nn(CCC(C)(C)O)c(C)c2cc1NC(=O)c1cccc(n1)C(F)(F)F

InChI Key InChIKey=NIVXKXJUPHEDHS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633514   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer

Curated by ChEMBL

LigandBDBM50633514(CHEMBL5412519)Copy SMILESCopy InChI

Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human IRAK4 expressed in baculovirus infected Hi-5 cells using biotinylated-Ahx-KKARFSRFAGSSPSQASFAEP...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Bayer

Curated by ChEMBL

LigandBDBM50633514(CHEMBL5412519)Copy SMILESCopy InChI

Affinity DataIC50: 2.17E+5nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human FLT3 (564 to end residues) expressed in Sf21 cells using biotinylated-Ahx-GGEEEEYFELVKKKK pepti...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL