BDBM50633515 CHEMBL5405768

SMILES CC(C)(CCc1nc2cc(c(cc2n1C)NC(=O)c3cccc(n3)C(F)(F)F)C(C)(C)O)O

InChI Key InChIKey=HRMRCQCPDQTKCV-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633515   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bayer

Curated by ChEMBL

LigandBDBM50633515(CHEMBL5405768)Copy SMILESCopy InChI

Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human IRAK4 expressed in baculovirus infected Hi-5 cells using biotinylated-Ahx-KKARFSRFAGSSPSQASFAEP...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Bayer

Curated by ChEMBL

LigandBDBM50633515(CHEMBL5405768)Copy SMILESCopy InChI

Affinity DataIC50: 7.63E+5nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human FLT3 (564 to end residues) expressed in Sf21 cells using biotinylated-Ahx-GGEEEEYFELVKKKK pepti...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL