BDBM50633770 CHEMBL5405559

SMILES CCC(=O)N1CC2(CC(n3nc(C(=O)Nc4ccc5c(cnn5C)c4)c4cc(-c5cn[nH]c5)ccc43)C2)C1

InChI Key InChIKey=AMRWITUJPGPGGY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50633770   

TargetSon of sevenless homolog 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50633770BDBM50633770(CHEMBL5405559)
Affinity DataEC50:  4.37E+3nMAssay Description:Agonist activity at SOS1 in human HeLa cells expressing wild type KRAS assessed as increase in p-ERK level incubated for 30 mins by Western blot anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed