BDBM50634263 CHEMBL5412673

SMILES COc1cc(cc(OC)c1OC)C(=O)c1cn(-c2ccc(cc2)S(N)(=O)=O)c2ccccc12

InChI Key InChIKey=CLFJSQILDVYGBK-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50634263   

TargetCarbonic anhydrase 9(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634263(CHEMBL5412673)
Affinity DataKi:  7.30nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634263(CHEMBL5412673)
Affinity DataKi:  17nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634263(CHEMBL5412673)
Affinity DataKi:  68nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634263(CHEMBL5412673)
Affinity DataKi:  446nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed