BDBM50634305 CHEMBL5434863

SMILES [2H]C([2H])([#8]-c1nc(-[#7]-[#6]C2([#6]-[#6]-[#6]2)[#7](-[#6])-[#6])c2cnc(c(F)c2n1)-c1cc(-[#8])cc2ccc(F)c(C#C)c12)C12[#6]-[#6]-[#6]-[#7]1-[#6]\[#6](-[#6]2)=[#6](\F)F

InChI Key InChIKey=RDDQUVDVYKWTGG-FKUWIZNHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50634305   

TargetGTPase KRas(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50634305(CHEMBL5434863)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human GTP-bound KRAS wild type (1 to 169 residues) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed