BDBM50634565 CHEMBL5402068

SMILES c1ccc(cc1)C2=N[C@@H](C(=O)Nc3c2cccc3)NC(=O)c4ccccc4CN5CCOCC5

InChI Key InChIKey=NBCFKFUKUXVZQS-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50634565   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50634565(CHEMBL5402068)
Affinity DataIC50: 94nMAssay Description:Displacement of FAM-labeled probe from recombinant biotinylated Cbl-b (unknown origin) expressed in Escherichia coli BL21(DE3) Tuner cells by TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)