BDBM50634604 CHEMBL5414073

SMILES CC1(N)CCN(CC1)c1cnc2nc(Sc3cccn4nccc34)ccc2n1

InChI Key InChIKey=TWNUZAYFKPTMKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50634604   

LigandPNGBDBM50634604(CHEMBL5414073)
Affinity DataIC50: 401nMAssay Description:Allosteric inhibition of recombinant full length 6His-tagged SHP2 (2 to 527 residues) (unknown origin) expressed in Escherichia coli using DiFMUP as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
LigandPNGBDBM50634604(CHEMBL5414073)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of ERK1/2 phosphorylation at Thr202/Tyr204 residues in human KYSE520 cells incubated for 1 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed