BDBM50634678 CHEMBL5555747

SMILES CC[C@@H](N)c1cc(N2CCC[C@H]2C)cc2c1CN(c1cccc(-c3nnc4n3[C@@H](C)CC4)n1)C2=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50634678   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandPNGBDBM50634678(CHEMBL5555747)
Affinity DataKi: <0.0500nMAssay Description:Inhibition of HPK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandPNGBDBM50634678(CHEMBL5555747)
Affinity DataIC50: 17nMAssay Description:Inhibition of HPK1 (unknown origin) assessed as inhibition of SLP76 phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed