BDBM50634679 CHEMBL5505822

SMILES CC(C)(O)Cn1nccc1-c1ccc2cc1N[C@H](CO)c1ccccc1OCCCCc1cc(ccc1C#N)N2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50634679   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandPNGBDBM50634679(CHEMBL5505822)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of HPK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandPNGBDBM50634679(CHEMBL5505822)
Affinity DataIC50: 600nMAssay Description:Inhibition of HPK1 (unknown origin) assessed as inhibition of SLP76 phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed