BDBM50634820 CHEMBL5559023::US20250353833, Inhibitor MFE-2022-101

SMILES CN(C)c1cccc2c(S(=O)(=O)NCCOCCOC(=O)NC34CC5CC(CC(NCC(=O)N6Cc7ccc(F)cc7C6)(C5)C3)C4)cccc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50634820   

TargetDipeptidyl peptidase 9(Human)
UNIVERSITEIT ANTWERPEN

US Patent
LigandChemical structure of BindingDB Monomer ID 50634820BDBM50634820(CHEMBL5559023 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 0.00400nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/10/2026
Entry Details US Patent

TargetDipeptidyl peptidase 8(Human)
UNIVERSITEIT ANTWERPEN

US Patent
LigandChemical structure of BindingDB Monomer ID 50634820BDBM50634820(CHEMBL5559023 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 0.0660nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/10/2026
Entry Details US Patent

TargetDipeptidyl peptidase 9(Human)
UNIVERSITEIT ANTWERPEN

US Patent
LigandChemical structure of BindingDB Monomer ID 50634820BDBM50634820(CHEMBL5559023 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant human DPP9More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 8(Human)
UNIVERSITEIT ANTWERPEN

US Patent
LigandChemical structure of BindingDB Monomer ID 50634820BDBM50634820(CHEMBL5559023 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human DPP8More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634820BDBM50634820(CHEMBL5559023 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human DPP2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634820BDBM50634820(CHEMBL5559023 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PREPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634820BDBM50634820(CHEMBL5559023 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
University of Antwerp

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634820BDBM50634820(CHEMBL5559023 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human FAPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed