BDBM50634827 CHEMBL5558204::US20250353833, Inhibitor MFE-2022-119

SMILES O=C(CCCCC1SCC2NC(=O)NC21)NCCOCCNC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50634827   

TargetDipeptidyl peptidase 9(Human)
UNIVERSITEIT ANTWERPEN

US Patent
LigandChemical structure of BindingDB Monomer ID 50634827BDBM50634827(CHEMBL5558204 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 0.0500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/10/2026
Entry Details US Patent

TargetDipeptidyl peptidase 8(Human)
UNIVERSITEIT ANTWERPEN

US Patent
LigandChemical structure of BindingDB Monomer ID 50634827BDBM50634827(CHEMBL5558204 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 0.541nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/10/2026
Entry Details US Patent

TargetDipeptidyl peptidase 9(Human)
UNIVERSITEIT ANTWERPEN

US Patent
LigandChemical structure of BindingDB Monomer ID 50634827BDBM50634827(CHEMBL5558204 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human DPP9More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 8(Human)
UNIVERSITEIT ANTWERPEN

US Patent
LigandChemical structure of BindingDB Monomer ID 50634827BDBM50634827(CHEMBL5558204 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 541nMAssay Description:Inhibition of recombinant human DPP8More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634827BDBM50634827(CHEMBL5558204 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human DPP2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
University of Antwerp

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634827BDBM50634827(CHEMBL5558204 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human FAPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634827BDBM50634827(CHEMBL5558204 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634827BDBM50634827(CHEMBL5558204 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PREPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed