BDBM50634991 CHEMBL5555216
SMILES N#Cc1ccccc1NC(=O)Cn1nc(-c2ccccc2)c(-c2ccccc2)nc1=O
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50634991
TargetBeta-secretase 1(Human)
Indian Institute of Technology - Banaras Hindu University
Curated by ChEMBL
Indian Institute of Technology - Banaras Hindu University
Curated by ChEMBL
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of human BACE-1 using (7-Methoxycoumarin-4-acetyl-[Asn670, Leu671]-Amyloid beta/A4 precursor protein 770 fragments 667-676- (2, 4-dinitrop...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Indian Institute of Technology - Banaras Hindu University
Curated by ChEMBL
Indian Institute of Technology - Banaras Hindu University
Curated by ChEMBL
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition by DTNB base...More data for this Ligand-Target Pair
TargetCholinesterase(Human)
Indian Institute of Technology - Banaras Hindu University
Curated by ChEMBL
Indian Institute of Technology - Banaras Hindu University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition by DTNB based Ellman's ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Indian Institute of Technology - Banaras Hindu University
Curated by ChEMBL
Indian Institute of Technology - Banaras Hindu University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Dyrk1A (unknown origin) incubated for 1 hrs in presence of [gamma-33P]-ATP by microplate scintillation counter based radiometric protei...More data for this Ligand-Target Pair