BDBM50635104 CHEMBL5517663

SMILES COc1cc2ncnc(N3CCN(Cc4ccccc4)CC3)c2cc1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50635104   

TargetBeta-secretase 1(Human)
Indian Institute of Technology-Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50635104(CHEMBL5517663)
Affinity DataIC50: 231nMAssay Description:Inhibition of human BACE-1 measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Indian Institute of Technology-Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50635104(CHEMBL5517663)
Affinity DataKi:  246nMAssay Description:Non-competitive inhibition of human AChE using acetylthiocholine iodide as substrate assessed as inhibition constant at 0.03 to 0.3 uM by Dixon plot ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Indian Institute of Technology-Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50635104(CHEMBL5517663)
Affinity DataIC50: 283nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Human)
Indian Institute of Technology-Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50635104(CHEMBL5517663)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed