BDBM50635108 CHEMBL5559245

SMILES COc1cc2ncnc(N3CCN(Cc4ccc(Cl)cc4)CC3)c2cc1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50635108   

TargetAcetylcholinesterase(Human)
Indian Institute of Technology-Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50635108(CHEMBL5559245)
Affinity DataIC50: 921nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Indian Institute of Technology-Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50635108(CHEMBL5559245)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of human BACE-1 measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Human)
Indian Institute of Technology-Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50635108(CHEMBL5559245)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed