BDBM50635116 CHEMBL5557978

SMILES CC1c2cc(Oc3ccccc3)ccc2N=C(N)N1CCCC(=O)N(Cc1ccnn1C)C1CCCCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50635116   

TargetBeta-secretase 1(Human)
Indian Institute of Technology-Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50635116(CHEMBL5557978)
Affinity DataIC50: 140nMAssay Description:Inhibition of BACE-1 in human SH-SY5Y cells transfected with human APP695 measured after 24 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Indian Institute of Technology-Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50635116(CHEMBL5557978)
Affinity DataIC50: 380nMAssay Description:Inhibition of C-terminal 10-His tagged recombinant human BACE-1 using Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2 as substrate p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed