BDBM50635800 CHEMBL5542350

SMILES COc1ccc(Nc2cc3c(cn2)n(C)c(=O)n3C2CCOCC2)c(C)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50635800   

TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50635800(CHEMBL5542350)
Affinity DataIC50: 8nMAssay Description:Inhibition of human DNA-PK using EPPLSQEAFADLWK as substrate in presence of ATP by kinase hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM50635800(CHEMBL5542350)
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of human PI3Kalpha using PI(4,5)P2:PS as substrate in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM50635800(CHEMBL5542350)
Affinity DataIC50: 6.82E+3nMAssay Description:Inhibition of human PI3Kdelta using PI(4,5)P2:PS as substrate in presence of ATP by kinase hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM50635800(CHEMBL5542350)
Affinity DataIC50: 8.83E+3nMAssay Description:Inhibition of human PI3Kbeta using PI(4,5)P2:PS as substrate in presence of ATP by kinase hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50635800(CHEMBL5542350)
Affinity DataIC50: 9.15E+3nMAssay Description:Inhibition of human full length recombinant ATM using GST-cMyc-p53 as substrate by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM50635800(CHEMBL5542350)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of human PI3Kgamma using PI(4,5)P2:PS as substrate in presence of ATP by kinase hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50635800(CHEMBL5542350)
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of human mTOR in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed