BDBM50635812 CHEMBL5543038

SMILES COc1ccc(Nc2cc3c(cn2)n(C)c(=O)n3C2CCNCC2)c(C)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50635812   

TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50635812(CHEMBL5543038)
Affinity DataIC50: 77nMAssay Description:Inhibition of human DNA-PK using EPPLSQEAFADLWK as substrate in presence of ATP by kinase hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM50635812(CHEMBL5543038)
Affinity DataIC50: 6.07E+4nMAssay Description:Inhibition of human PI3Kalpha using PI(4,5)P2:PS as substrate in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50635812(CHEMBL5543038)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human mTOR in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed