BDBM50635830 CHEMBL5517830

SMILES C=CC(=O)Nc1ccccc1Nc1ncc2c(n1)N(CCCN1CCN(C(=O)C=C)CC1)C(=O)N(c1c(Cl)c(OC)cc(OC)c1Cl)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50635830   

TargetFibroblast growth factor receptor 4(Human)
Jingzhou Hospital Affiliated to Yangtze University

Curated by ChEMBL
LigandPNGBDBM50635830(CHEMBL5517830)
Affinity DataIC50: 48nMAssay Description:Inhibition of N-terminal 6xHis-tagged human FGFR4 (445 to 753 residues) transfected in Escherichia coli Rossetta cells incubated for 30 mins by ADP-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Jingzhou Hospital Affiliated to Yangtze University

Curated by ChEMBL
LigandPNGBDBM50635830(CHEMBL5517830)
Affinity DataIC50: 193nMAssay Description:Inhibition of FGFR4 C477A mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Jingzhou Hospital Affiliated to Yangtze University

Curated by ChEMBL
LigandPNGBDBM50635830(CHEMBL5517830)
Affinity DataIC50: 602nMAssay Description:Inhibition of FGFR4 C552A mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Jingzhou Hospital Affiliated to Yangtze University

Curated by ChEMBL
LigandPNGBDBM50635830(CHEMBL5517830)
Affinity DataIC50: 977nMAssay Description:Inhibition of N-terminal 6xHis-tagged human FGFR3 (450 to 758 residues) transfected in Escherichia coli Rossetta cells incubated for 30 mins by ADP-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Jingzhou Hospital Affiliated to Yangtze University

Curated by ChEMBL
LigandPNGBDBM50635830(CHEMBL5517830)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of FGFR4 C552A/C477A double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Jingzhou Hospital Affiliated to Yangtze University

Curated by ChEMBL
LigandPNGBDBM50635830(CHEMBL5517830)
Affinity DataIC50: 2.41E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged human FGFR2 (453 to 770 residues) transfected in Escherichia coli Rossetta cells incubated for 30 mins by ADP-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Jingzhou Hospital Affiliated to Yangtze University

Curated by ChEMBL
LigandPNGBDBM50635830(CHEMBL5517830)
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged human FGFR1 (456 to 765 residues) transfected in Escherichia coli Rossetta cells incubated for 30 mins by ADP-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed