BDBM50635836 CHEMBL2032358

SMILES COc1ccc2[nH]c(C)c(/C=C/C(=O)c3ccncc3)c2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50635836   

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Sichuan University/West China School of Nursing

Curated by ChEMBL
LigandPNGBDBM50635836(CHEMBL2032358)
Affinity DataKd:  3.80nMAssay Description:Binding affinity to PIKfyve (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Sichuan University/West China School of Nursing

Curated by ChEMBL
LigandPNGBDBM50635836(CHEMBL2032358)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of N-terminal His-tagged human PIKfyve expressed in Sf9 insect cells incubated for 1 hr by enzyme assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Sichuan University/West China School of Nursing

Curated by ChEMBL
LigandPNGBDBM50635836(CHEMBL2032358)
Affinity DataKd:  5.30nMAssay Description:Binding affinity to PIKfyve (unknown origin) assessed as dissociation constant by KINOMEscan profiling methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed