BDBM50635905 CHEMBL5523420

SMILES COc1cc2cc(C(=O)NCCC3CCN(Cc4ccccc4)CC3)[nH]c2cc1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50635905   

TargetAcetylcholinesterase(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50635905(CHEMBL5523420)
Affinity DataKi:  260nMAssay Description:Mixed inhibition of recombinant human AChE expressed in HEK293 cells assessed as dissociation constant using acetylthiocholine iodide as substrate by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50635905(CHEMBL5523420)
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50635905(CHEMBL5523420)
Affinity DataIC50: 390nMAssay Description:Inhibition of human BACE-1 incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50635905(CHEMBL5523420)
Affinity DataKi:  460nMAssay Description:Mixed inhibition of human BACE-1 assessed as dissociation constant by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50635905(CHEMBL5523420)
Affinity DataIC50: 520nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50635905(CHEMBL5523420)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed