BDBM50635908 CHEMBL5559707

SMILES COc1ccc2[nH]cc(C(=O)NCCC3CCN(Cc4ccccc4)CC3)c2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50635908   

TargetAcetylcholinesterase(Electric eel)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50635908(CHEMBL5559707)
Affinity DataIC50: 720nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50635908(CHEMBL5559707)
Affinity DataKi:  920nMAssay Description:Mixed inhibition of equine serum BuChE assessed as dissociation constant using butyrylthiocholine iodide as substrate by Lineweaver-Burk plot analysi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50635908(CHEMBL5559707)
Affinity DataKi:  930nMAssay Description:Mixed inhibition of recombinant human AChE expressed in HEK293 cells assessed as dissociation constant using acetylthiocholine iodide as substrate by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50635908(CHEMBL5559707)
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50635908(CHEMBL5559707)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BACE-1 incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed