BDBM50635957 CHEMBL5556905

SMILES C[C@@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(S(=O)(=O)c2cc[nH]n2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50635957   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635957(CHEMBL5556905)
Affinity DataIC50: 160nMAssay Description:Inhibition of human ATR/ATRIP using GST-tagged p53 as substrate in presence of 3 uM ATP by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635957(CHEMBL5556905)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ATR in human HeLa S3 cells assessed as decrease in CHK1 phosphorylation at Ser345 residue pretreated for 20 mins followed by gemcitabin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed