BDBM50636025 CHEMBL5559823

SMILES N#Cc1ccccc1CN1CCC(Nc2c(-c3cn[nH]c3)cnc3[nH]ccc23)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50636025   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50636025(CHEMBL5559823)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of TYK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50636025(CHEMBL5559823)
Affinity DataIC50: 155nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50636025(CHEMBL5559823)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50636025(CHEMBL5559823)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed