BDBM50636218 CHEMBL5559689

SMILES CCOCC1(COCC)CCC(c2n[nH]cc2CN(C)CCNC)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50636218   

TargetProtein arginine N-methyltransferase 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50636218(CHEMBL5559689)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of N-terminal GST-tagged human PRMT3 (2 to end residues) expressed in Escherichia coli using SAM and Histone (1 to 21 residues) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50636218(CHEMBL5559689)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PRMT1 (unknown origin) using SAM and histone (1 to 21 residues) as substrate preincubated for 60 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 8(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50636218(CHEMBL5559689)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PRMT8 (unknown origin) using SAM and Histone (1 to 21 residues) as substrate preincubated for 60 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50636218(CHEMBL5559689)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of N-terminal His tagged human recombinant PRMT6 (2 to 375 residues) expressed in Escherichia coli using SAM and Histone (1 to 21 residues...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50636218(CHEMBL5559689)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of N-terminal FLAG tagged human PRMT4 (2 to end residues) expressed in FreeStyle 293-F cells using SAM and rHistone H3.1 as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50636218(CHEMBL5559689)
Affinity DataIC50: 3nMAssay Description:Inhibition of PRMT1 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50636218(CHEMBL5559689)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50636218(CHEMBL5559689)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PRMT1 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50636218(CHEMBL5559689)
Affinity DataIC50: 10nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50636218(CHEMBL5559689)
Affinity DataIC50: 12nMAssay Description:Inhibition of CARM1 (unknown origin) using histone H3 (21 to 44 residues) and SAM as substrates by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed