BDBM50636251 CHEMBL5532212

SMILES COC(=O)c1ccc(COc2ccc(C3NCCc4c3[nH]c3ccccc43)cc2OC)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50636251   

TargetProtein arginine N-methyltransferase 5(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50636251(CHEMBL5532212)
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of PRMT5 (unknown origin) by radiometric-based scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50636251(CHEMBL5532212)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of wild type GST-tagged EGFR catalytic domain (unknown origin) expressed in insect cells using poly(Glu-Tyr) as substrate incubated for 6 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50636251(CHEMBL5532212)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT4 (unknown origin) preincubated for 15 mins followed by substrate addition and measured after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50636251(CHEMBL5532212)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT1 (unknown origin) using [3H]SAM as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed