BDBM50636262 CHEMBL5555046

SMILES COc1cc(C2NCCc3c2[nH]c2ccccc32)ccc1OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50636262   

TargetProtein arginine N-methyltransferase 5(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50636262(CHEMBL5555046)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of PRMT5 (unknown origin) by radiometric-based scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50636262(CHEMBL5555046)
Affinity DataIC50: 1.93E+4nMAssay Description:Inhibition of wild type GST-tagged EGFR catalytic domain (unknown origin) expressed in insect cells using poly(Glu-Tyr) as substrate incubated for 6 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50636262(CHEMBL5555046)
Affinity DataIC50: 8.65E+4nMAssay Description:Inhibition of wild type GST-tagged HER4 catalytic domain (unknown origin) expressed in insect cells using poly(Glu-Tyr) as substrate incubated for 6 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50636262(CHEMBL5555046)
Affinity DataIC50: 8.76E+4nMAssay Description:Inhibition of PRMT4 (unknown origin) preincubated for 15 mins followed by substrate addition and measured after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50636262(CHEMBL5555046)
Affinity DataIC50: 9.82E+4nMAssay Description:Inhibition of wild type GST-tagged HER2 catalytic domain (unknown origin) expressed in insect cells using poly(Glu-Tyr) as substrate incubated for 6 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50636262(CHEMBL5555046)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT1 (unknown origin) using [3H]SAM as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed