BDBM50636320 CHEMBL5523449

SMILES CCOc1cccc2cc(/C(C)=N/Nc3nc(-c4ccc(OC)cc4)cs3)c(=O)oc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50636320   

TargetVascular endothelial growth factor receptor 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50636320(CHEMBL5523449)
Affinity DataIC50: 35nMAssay Description:Inhibition of hypoxia induced VEGFR-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50636320(CHEMBL5523449)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of human CA9 preincubated for 6 hrs by phenol red staining based stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50636320(CHEMBL5523449)
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of human CA12 preincubated for 6 hrs by phenol red staining based stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50636320(CHEMBL5523449)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human CA2 preincubated for 6 hrs by phenol red staining based stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Tanta University

Curated by ChEMBL
LigandPNGBDBM50636320(CHEMBL5523449)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human CA1 preincubated for 6 hrs by phenol red staining based stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed