BDBM50636546 CHEMBL5557001

SMILES FC(F)(F)c1ccc(Cl)cc1CSc1nnc(-c2cnccn2)o1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50636546   

TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636546(CHEMBL5557001)
Affinity DataEC50:  550nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed