BDBM50636699 CHEMBL5559947

SMILES COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OCCCCNCc1c(OC)cc(OCc2cccc(-c3ccccc3)c2C)cc1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50636699   

TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50636699(CHEMBL5559947)
Affinity DataIC50: 38nMAssay Description:Inhibition of EGFR (cytoplasmic domain from 669 to 1210) (unknown origin) using Tk-peptide substrate pretreated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50636699(CHEMBL5559947)
Affinity DataKd:  520nMAssay Description:Binding affinity to recombinant mouse His-tagged PD-L1 expressed in HEK293 cells by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50636699(CHEMBL5559947)
Affinity DataKd:  580nMAssay Description:Binding affinity to recombinant human PD-L1 expressed in HEK293 cells by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50636699(CHEMBL5559947)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction assessed as inhibition rate incubated for 1 hr by HTRF assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed